91°µÍø

Graduate School of Biomedical Sciences

Faculty

Primary Training Faculty

  (Endodontics) – modulation of inflammatory and neuropathic pain

  (Cellular & Integrative Physiology) – Drosophila as a genetic model for neurodevelopmental and neurodegenerative disorders

(TBRI) – Neuroinflammation in the neural consequences of encephalitic arbovirus and other viral diseases

  (Pharmacology) – G protein - coupled receptors, signal transduction, ligand functional selectivity

  (Cellular & Integrative Physiology) – molecular neuron-glia interactions, synaptic development and neurological disorders

 (Cancer Therapy and Research Center) – Neuro-oncology; overcoming resistance to cancer therapy driven by the hypoxic microenvironment

  (Biochemistry and Structural Biology) - DNA repair and therapy resistance in glioblastoma

  (Neurology) – hippocampal plasticity; mechanisms of neuronal hyperexcitability, epilepsy

(Physiology) – endocannabinoid signaling and neuroinflammation in neurodegenerative disease and TBI

  (Cell Systems and Anatomy) – Genetic regulation of neuronal responses to aging and injury

(Molecular Medicine) – mammalian vision and retinal physiology

  (Pharmacology) – molecular and cellular mechanisms of drug efficacy and differential signal transduction 

  (Cell Systems and Anatomy) – develop neural stem cells for therapeutic use in Parkinson’s and other diseases

  (Cellular & Integrative Physiology) – regulation of monoamine transporters, psychotherapeutic drug effects 

. (Endodontics) – Peripheral modulation of pain and inflammation; bioengineering and stem cells

(Biggs Inst.) – mechanisms and treatment of severe brain disorders; neuromodulatory therapies

(Biochemistry and Structural Biology) - Regulation of phospholipase enzymes by upstream signaling pathways

  (Biochemistry and Structural Biology) – computational tools to study genetic and environmental factors in Alzheimer’s Disease and other neurodegenerative disorders

 (Research Imaging Institute) – Non-invasive functional and structural neuroimaging in humans, non-human primates and rodents 

  (Pharmacology) – behavioral and pharmacological factors influencing the abuse liability of drugs

(Cell Systems & Anatomy) – translational studies on the role of chronic stress in Alzheimer’s disease risk and neuropathology

 (Psychiatry) – neuroimaging to understand changes in brain function with psychotherapy for youth with PTSD

  (Psychiatry) – Mechanisms of alcohol abuse and recovery; behavioral pharmacology of synthetic cannabinoids

  (Neurology) – Brain injury and motor system recovery after stroke and cerebral amyloid angiopathy

(Cellular & Integrative Physiology) – serotonin and social behavior

 (Biochemistry) –role of sulfatide and myelin lipids in the pathogenesis of Alzheimer’s Disease and aging

  (Endodontics) – neuropharmacology of primary nociceptors and pain sensitivity

(Pharmacology) – genetic, cellular and molecular mechanisms of developmental neuropsychiatric disorders

(Pharmacology) – microglia and neuroinflammation in Alzheimer’s Disease; tau and calcium regulation

  (Oral and Maxillofacial Surgery) – biochemical modulation of peripheral pain in nociceptive neurons by regulation of TRPV1 channel function

 (Endodontics) - extracellular vesicles in pain; new diagnostics; pain management

 (Biochemistry) - structural regulation of glutamate receptor function

  (Cell Systems and Anatomy) – molecular and cellular regulation of neural stem cells and adult neurogenesis

  (Cell Systems and Anatomy) – mitochondrial calcium regulation in cell death and survival in the aging process

  (Cellular & Integrative Physiology) – ion channel dysregulation in mouse models of FXS and other developmental disorders

  (Pharmacology) – Hippocampal and other afferent regulation of mesolimbic dopamine activity

  (Pharmacology) – Functional genomics of neuropsychiatric and neurologic diseases; human iPS cell models

  (Pharmacology) - Behavioral pharmacology; abuse potential of drugs; treatment of substance use disorders

  (Pharmacology) – Effect of stress on behavior and brain function; novel therapeutics; cancer therapy-induced cognitive impairment

  (Pharmacology) – Tryptophan metabolism and mechanisms linking neuroinflammation and depression 

(Barshop Institute) – lipidomics; role of ceramides in Alzheimer’s Disease

  (Cellular & Integrative Physiology) – Role of calcium signaling and neuron-astroglial interactions in neuromodulation and arousal

Pharmacology) – neural circuit mechanisms of mood disorders and psychosis in perimenopause and menopause

  (Cellular & Integrative Physiology) – Axonal plasticity, cellular computation and signal processing in neural circuits

   (Cell Systems and Anatomy) – role of mitochondrial oxidative stress in aging and Alzheimer’s Disease

(Biggs Inst.) - molecular biomarkers and their connection to genomics of Alzheimer’s Disease

 (Endodontics) – Pain, analgesia, inflammation; Stem cells and regenerative endodontics in pain modulation

   (Endodontics) – mechanisms and novel treatment approaches for oral cancer pain

 (Biggs Inst.) – genetic mechanisms in Alzheimer’s Disease and other dementias

   (Neurosurgery) – role of astrocyte lipoprotein metabolism in recovery from stroke and traumatic brain injury

  (Cellular & Integrative Physiology) – ion channel physiology; regulation by intracellular signaling pathways and excitability 

  (Cellular & Integrative Physiology) – role of mTOR signaling in oligodendrocyte development and diseases of myelination

(Cellular and Integrative Physiology) – mechanisms of cellular senescence and its role in neurodegeneration

Affiliated Faculty

   (Cell Systems and Anatomy) – mitochondrial deficits and mtDNA mutations in neurodegeneration and aging

(Neuroscience, UTSA) – genetic and epigenetic factors in neurologic and psychiatric disorders

 (Pharmacology) – novel therapies for stress-related psychiatric disorders 

  (Medicine) – Cellular and molecular mechanisms of neutrophil signal transduction and activation; transcriptional regulation of genes relevant to biology of aging 

   (Cellular & Integrative Physiology) – pluripotent stem cells and regenerative medicine in neurodegenerative disease models

(Neuroscience, UTSA) – genetic epilepsies; adult neurogenesis & epilepsy; iPSC models and human brain organoids

  (Biochemistry and Structural Biology) – function and regulation of gap junctions; connexins in cell signaling and development

  (Biochemistry and Structural Biology) – structure of gap junctions; genetic and structural diversity of connexins in disease

   (Cell Systems and Anatomy) – RNA binding proteins and miRNA regulating gene expression in neuronal stress

  (Neurology) – genetic, neuroimaging and behavioral aspects of epilepsy

  (Cell Systems and Anatomy) – mechanisms of tumorigenesis and neural development in neurofibromatosis

(Neuroscience, UTSA) – neurobiology of motivated behavior; stress; addiction

91°µÍø

Graduate School of Biomedical Sciences

7703 Floyd Curl Drive
San Antonio, TX 78229
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91°µÍø Health Science Center is the academic health center of 91°µÍø. It includes schools of medicine, dentistry, nursing, health professions, graduate biomedical sciences and public health, and a clinical enterprise called UT Health San Antonio, which conducts 2.5 million patient visits yearly.

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